Nature

Controlling for Confounding Effects in Single Cell RNA Sequencing Studies Using both Control and Target Genes

Single cell RNA sequencing (scRNAseq) technique is becoming increasingly popular for unbiased and high-resolutional transcriptome analysis of heterogeneous cell populations. Despite its many ...
Nature

Critical appraisal of confounding factors of observational studies on the association between dentofacial features and dental trauma in a Brazilian population

Dental trauma is a highly prevalent dental emergency. Children and adolescents without inadequate lip coverage, increased overjet, and anterior open bite are associated with the occurrence of ...
Simon Fraser University

Example 15.12: Replicated Blocked Design with Partial Confounding

In an unreplicated blocked design, the interaction effect that is confounded with the block effect cannot be estimated. You can replicate the experiment so that a ...
CMAJ

Testing group differences for confounder selection in nonrandomized studies: flawed practice

Using observed imbalances between study groups (e.g., exposed and unexposed) to determine variables for confounding adjustment in nonrandomized studies may misguide the selection of variables to ...