Christina A. Sheil, MD, explains why polypharmacy has become one of the most significant challenges in modern healthcare.

Modeling complex systems When studying complex biological systems such as the immune system, scientists can extract many different types of data. Sequencing cell genomes tells them which gene variants ...

The beautiful, fascinating and often perplexing world around us grows from intricate and convoluted interactions of millions of pieces. As scientists, we work to understand and describe the parts and ...

Systems biology is a rapidly evolving discipline that examines the complex interactions underlying biological function ...

Ever better experimental techniques allow us to perform experiments under tightly controlled conditions and can deliver gigantic amounts of data reflecting the complexity of biology. This has vastly ...